Gunjan Lab Jerome Irianto PhD Cancer mechanobiology and genomics Irianto Lab Mohamed Kabbaj PhD Epigenetics of social behaviors and neurobiology of sex differences in anxiety and depression Kabbaj Lab Sanjay Kumar PhD Synaptic physiology underlying cortical function and epilepsy Kumar Lab Eric Laywell PhD
We are a cellular biophysics lab with particular interests in cell biology cancer and genomics
Jerome Irianto 1 Charlotte R Pfeifer 1 Irena L Ivanovska 1 Joe Swift 1 Dennis E Discher 1 Affiliation 1 Molecular and Cell Biophysics Lab University of Pennsylvania Philadelphia PA 19104 USA PMID 27570565 PMCID PMC4999255 DOI 101007s1219501604378 Abstract Dysmorphic nuclei are commonly seen in cancers and provide strong
Irianto Lab
Our lab aims to dissect the progression of cancer from mechanobiology perspective the interplay between tumor cells and their physical environment can provide us biological insights on novel drug targets What is the impact of cancer metastasis on cellular phenotypes During metastasis
Nuclear lamin stiffness is a barrier to 3D migration but PubMed
Irianto J et al DNA damage follows repair factor depletion and portends genome variation in cancer cells after pore migration Molecular and Cell Biophysics Lab 129 Towne Building
Jerome Irianto PhD Florida State University
Irianto Lab
Irianto Lab Team
Faculty Research Labs College of Medicine
Nuclear lamins in cancer PubMed
Irianto Lab Research
Irianto Lab page Mechanobiology has been the common theme throughout Dr Irianto research career His graduate work looked at the consequence of osmotic challenge on chondrocytes He discovered that alterations in osmolality leads to changes in chromosome condensation state that dictate nuclear enzymes accessibility and translates to changes in
Mitotic progression following DNA damage enables pattern Nature
Irianto Lab
Irianto Lab Publication
Shane M Harding 1 Joseph L Benci 2 3 4 Jerome Irianto 5 6 7 Dennis E Discher 5 6 7 Andy J Minn 2 3 4 Roger A Greenberg 1 Affiliations 1 Department of Cancer Biology Basser Center for BRCA Abramson Family Cancer Research Institute Perelman School of Medicine University of Pennsylvania 421 Curie Boulevard Philadelphia
Dr Jerome Irianto Assistant Professor Biomedical Sciences Office Medical Research Building Suite 3350B Tel 8506459438 Email jeromeiriantomedfsuedu
Mitotic progression following DNA damage enables pattern recognition
Jerome Irianto Assistant Professor Florida State University Cited by 2255 Cell Biology Mechanobiology Cancer biology Biophysics
Takamasa Harada 1 Joe Swift Jerome Irianto JaeWon Shin Kyle R Spinler Avathamsa Athirasala Rocky Diegmiller P C Dave P Dingal Irena L Ivanovska Dennis E Discher Affiliation 1 Molecular and Cell Biophysics Lab and 2 Cell and Molecular Biology Graduate Group University of Pennsylvania Philadelphia PA 19104 PMID 24567359